weakness
cough
labored breathing
fatigue
pneumonia
intermittent fever
arthritis
muscle wasting
discharge from nose or eye
depression
weight loss
anorexia
increased thirst and urination
incontinence
sensitivity of the skin
head tremors
disorientation
seizures
neck or back pain
bleeding tendencies
pallor due to anemia
retinal hemorrhages
bleeding into the skin
rash
nose bleeds
spontaneous bleeding
abdominal tenderness
swelling of the legs
swollen lymph nodes

Certain features of ehrlichiosis may mimic the following diseases:

systemic lupus erythematosus
brucellosis
blastomycosis
endocarditis
immune mediated diseases
thrombocytopenia
pancytopenia
myelophthisis
cancer of the spleen or liver
Valley Fever
plasma cell myeloma
leukemia

From Dr. Stack's paper on erlichia (bold added)


QUOTE
Ehrlichia testing is done with antibody titers. Titers measure the body's immune response to
the bug, not the amount of bug in the dog's body. Most labs titer from 1:20 to 1:1,000,000 or
more. In general, the more chronic the infection, the higher the titer. The IDEXX in-office
"combo" test (heartworm/Lyme/Ehrlichia) catches titers over 1:100. While sick dogs usually
test positive, they might not if:
1. They have a poor immune response (the reason why a very sick dog sometimes tests
negative).

2. They carry an Ehrlichia strain other than the standard E. canis the lab tests for.

3. They have a titer <1:100 on the IDEXX test, or

4. There is variation between labs.There is not necessarily a correlation between the severity of the disease and the titer number.
All positive titers should be treated.
Ehrlichia dogs respond dramatically and quickly (within days) to doxycycline dosed at 5 mg per
pound twice daily. For this reason, greyhounds should be started on doxycycline as soon as
Ehrlichia is suspected. If not immediately available at the veterinary office, all human
pharmacies carry doxycycline (a tetracycline family antibiotic). Often patients are vastly
improved by the time their titer results are back from the lab. This doxycycline trial can be as
useful as the titer results in determining whether to continue with treatment. The standard
regimen we use in Arizona where Ehrlichia is endemic is 5 mg per pound twice daily for 2
months. Doxycycline must always be given with food - otherwise it may upset the stomach.